Improving antidepressant drugs: update on recently patented compounds

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Improving antidepressant drugs: update on recently patented compounds.

BACKGROUND According to the WHO, depression is a common condition that affects about 121 million people worldwide. Although the pathophysiological origin of this condition is still unknown, most of the known antidepressants enhance the extracellular availability of brain monoamines (serotonin and/or noradrenaline). OBJECTIVE/METHOD We have searched for the potential drugs and targets addresse...

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Pharmacogenetics of Antidepressant Drugs: An Update

Pharmacological treatment of depressive disorders is characterized by poor predictability of individual response. In recent years, the increasing evidence has demonstrated that genetic factors play a critical role in determining the differences in treatment outcome to antidepressant drugs. A number of pharmacogenetic studies on antidepressant drugs has been conducted, and genetic variations at ...

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Antidepressant Drugs

Depression is a common mental disorder characterized by sadness, loss of interest or pleasure, feelings of guilt or low self-esteem, sleep or appetite disturbances, fatigue and lack of concentration. The disorder can be either chronic or recurrent, substantially reducing the individual’s capacity to work or study, or perform the activities of daily living [1]. Depression is more common in women...

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Update on antidepressant use during breastfeeding.

QUESTION Many of my patients who are diagnosed with postpartum depression want to continue breastfeeding. How safe are the newer antidepressant medications during breastfeeding? ANSWER The newer antidepressants transfer into breast milk in low amounts and have not been associated with serious adverse events. Therefore, the antidepressant most effective for the woman should be considered.

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ژورنال

عنوان ژورنال: Expert Opinion on Therapeutic Patents

سال: 2009

ISSN: 1354-3776,1744-7674

DOI: 10.1517/13543770902932934